Anti-Beta NGF (Nerve Growth Factor) Neutralizing Antibody
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Catalog #
100436
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$355
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Description
Anti-beta NGF Neutralizing Recombinant Human antibody. This antibody has not been tested for cross reactivity with other species.
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Synonyms
Anti Nerve Growth Factor
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Product Data Gallery
The Anti-NGF Antibody was evaluated using TrkA-SRE (Luc)- HEK293 cell line (BPS Bioscience #79798). NGF (500 pM at final concentration) was incubated with various concentrations of Anti-NGF Antibody in the assay medium (Opti-MEM) for 45 min. at room tempe
Product Info
Storage and Usage
Citations
Species
Human
Isotype
IgG1
Clonality
Monoclonal
Host Species/Expression System
HEK293
Supplied As
Aqueous buffer solution.
Purification
Protein A affinity purification
from HEK293 supernatants.
Formulation
8 mM phosphate, 110 mM NaCl, 2.2 mM KCl, pH 7.4, and 20% glycerol.
UniProt #
P01138
Background
Beta NGF is a neurotrophic factor (NTF) that is involved in growth, proliferation and survival of neurons. AntiNGF monoclonal antibodies are in clinical trials as a chronic pain control medicine.
References
1. Norman, B.H. et al., J. Med. Chem. 2017; 60(1): 66-88.
2. Lane, N.E., et al., N. Engl. J. Med. 2010; 363(16): 1521-1531.
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