Anti–SETD8 polyclonal antibody
Catalog #
25315
$335
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Purchase
Description
Polyclonal antibody raised in rabbit against human SETD8 (SET domain containing 8), using the full length protein containing a Flag–tagged N–terminus and a His–tagged C terminus.
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Synonyms
SET07, SET8, PR/SET07, KMT5A, PR–Set7
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Product Data Gallery
Product Info
Storage and Usage
Citations
Clonality
polyclonal
Host Species/Expression System
Rabbit
Purification
Protein G purified
Format
Aqueous buffer solution
Formulation
PBS containing 0.05% azide and 0.05% ProClin 300.
Concentration
50 µg/25 µl
Immunogen
recombinant protein
Background
SETD8 (UniProtKB/Swiss–Prot entry Q9NQR1) is a histone methyl transferase that specifically monomethylates Lys–20 of histone H4. This histone modification represents a specific tag for epigenetic transcriptional repression en is enriched during mitosis. SETD8 may also play a role in maintaining silent chromatin by preventing the acetylation of the H4 tail.