CD38 (Pig) Fluorogenic Assay Kit (Hydrolase Activity)
The Pig CD38 Inhibitor Screening Assay Kit (Hydrolase Activity) is designed to measure the glycohydrolase activity of porcine CD38 for screening and profiling applications. In addition, the kit includes the CD38 inhibitor apigenin for use as a control inhibitor.
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Adjustable micropipettor and sterile tips
Fluorescent microplate reader
Rotating or rocker platform
| Catalog | Name | Amount | Storage |
| 101019 | CD38 (Pig) | 25 μg | -80°C |
| 4x CD38 hydrolase buffer | 4 ml | -20°C | |
| CD38 substrate (ε-NAD) | 200 μl | -20°C | |
| Apigenin (50 mM in DMSO) | 10 μl | -20°C | |
| 79685 | Black 96-well plate | 1 | Room Temp |
| Plate sealing film | 2 | Room Temp |
CD38, a differentiation antigen of B lymphocytes, is a type II integral membrane protein that functions as an ADP-ribosyl cyclase and nicotinamide adenine dinucleotide (NAD) glycohydrolase. The main enzymatic activity of CD38 is the hydrolysis of NAD. Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in various cells, including pancreatic ß cells. CD38 is a prognostic biomarker for acute B lymphoblastic leukemia.
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