PRMT7, His-FLAG-tag Recombinant
Catalog #
51054
$450
*
●
●
Purchase
Description
Human PRMT7 (protein arginine methyltransferase 7), GenBank Accession No. NM_019023, a.a. 2-692(end) with N-terminal His-FLAG-tag, MW=80 kDa, expressed in Sf9 cells using a Baculovirus expression system.
This product has been cited 3 times.
●
Synonyms
protein arginine N-methyltransferase 7, PRMT7, Histone-arginine N-methyltransferase7, PRMT-7
●
Product Data Gallery
4-20% SDS-PAGE Coomassie Staining
PRMT7 (Automethylation) inhibition curve using an AlphaLISA assay (#79721). Representative data only; data may vary by lot.
Product Info
Storage and Usage
Citations3
Species
Human
Host Species/Expression System
Sf9 insect cells
Purity
≥90%
Format
Aqueous buffer solution
Formulation
40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 80 µg/ml FLAG peptide, 3 mM DTT, 20% glycerol
MW
80 kDa
Amino Acids
2–692(end)
Genbank #
NM_019023,
UniProt #
Q9NVM4
Background
Three types of arginine methylation exist in mammalian cells: monomethylarginine (MMA), asymmetric dimethylarginine (ADMA) and symmetric dimethylarginine (SDMA). Type I PRMTs ((CARM1, PRMT1, PRMT2, PRMT3, PRMT6, and PRMT8) catalyze ADMA, while type II PRMTs (e.g. PRMTs 5 and 7) catalyze SDMA. Type II PRMTs are found to be strongly implicated in diseases like cancer. For example, PRMT5 plays a role in the repression of certain tumor suppressor genes such as RB tumor suppressors while PRMT7 overexpression is observed in breast cancer
References
1. Miranda, T.B., et al. J. Biol. Chem. 2004 May 28,279(22):22902-7
2. Lee, J.H., et al. J. Biol. Chem. 2005 Feb 4,280(5):3656-64.
2. Lee, J.H., et al. J. Biol. Chem. 2005 Feb 4,280(5):3656-64.
Powered by Bioz
6405 Mira Mesa Blvd. Suite 100
San Diego, CA 92121
858-202-1401
San Diego, CA 92121
858-202-1401
Products are for Research Use Only
COMPANY
Copyright © 2024
BPS Bioscience, Inc.
All rights reserved.
Diagrams on this website are created with BioRender.com.