TYK2 (JH2 domain), FLAG-Tag Recombinant

Catalog #

100523

$375 *

Size: 20 µg

Qty

Bulk/Custom

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Description

Human recombinant TYK2 (Non-receptor tyrosine-protein kinase TYK2), encompassing amino acids 575-869 containing pseudo-kinase domain JH2. This construct contains an N-terminal Flag-tag. The recombinant protein was affinity purified.

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Synonyms

Human Tyrosine Kinase 2 (TYK2), JTK1, IMD35, Non-Receptor Tyrosine-Protein Kinase TYK2, JAK family

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Product Data Gallery

4-20% SDS-PAGE Coomassie Staining

TYK2 (JH2 Domain) Activity

Product Info

Storage and Usage

Citations

Species

Human

Construct

TYK2 (JH2 domain), (FLAG-575-869)

Host Species/Expression System

Sf9

Purity

≥80%

Format

Aqueous Buffer Solution

Formulation

40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 0.04% Tween-20, 20% glycerol, and 3 mM DTT

34 kDa

Amino Acids

575-869

Genbank #

NM_003331

UniProt #

P29597

Tag(s)

N-terminal FLAG-tag

References

1. Myers, M.P. et al., JBC., 2001 Dec; 276: 47771-47774.
2. Karahhiosoff, M., et al., Immunity, 2000 Oct; 13(4): 549-560.

Storage/Stability

At least 6 months at –80°C.

Assay Conditions

Assay was done according to TYK2 JH2 Pseudokinase Domain Inhibitor Screening Assay Kit (BPS Bioscience #78107) with various amounts of TYK2 (JH2 Domain).

Instructions for Use

Thaw on ice and gently mix prior to use. DO NOT VORTEX. Perform a quick spin before opening. Aliquot into small volumes and flash freeze for long term storage. Avoid multiple freeze/thaw cycles.

Applications

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling

Shipping Temperature

-80°C

Warnings

Avoid freeze/thaw cycles.

Scientific Category

Kinase

Regulatory Status

Research Use Only

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Datasheets/Protocols

100523 Lot 220112-A

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TYK2 (JH2 domain), FLAG-Tag Recombinant

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