JNK1-β1(K55M), Kinase Deficient, GST-tag Recombinant
Catalog #
40871
$405
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Description
Human JNK1-β1(K55M), also known as MAPK8 (K55M) (GenBank Accession No. NM_139046), full length with mutation of lysine55 to methionine, and N-terminal GST-tag, MW=~70 kDa, expressed in E. coli. The K55M mutation prevents ATP binding, making the kinase inactive.
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Synonyms
JNK1b, mitogen-activated protein kinase 8, MAPK8b, Stress-Activated Protein Kinase, SAPK, JNK-1
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Product Data Gallery
Product Info
Storage and Usage
Citations
Species
Human
Host Species/Expression System
E. coli
Purity
≥85%
Format
Aqueous buffer solution
Formulation
45 mM Tris-HCl, pH 8.0, 124 mM NaCl, 2.4 mM KCl, 10% glycerol, and 3 mM DTT.
MW
~70 kDa
Amino Acids
full length
Specific Activity
inactive
Genbank #
NM_139046
UniProt #
P45983
References
1. Derijard, B. et al., Cell. 76(6):1025-37 (1994).
2. Kolodziejczyk, S M. et al., Curr. Biol. 11(16):1278-82 (2001).
2. Kolodziejczyk, S M. et al., Curr. Biol. 11(16):1278-82 (2001).