FcRn (FCGRT/B2M), His-Tag Recombinant
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Catalog #
71285
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Description
Recombinant human complex of FcRn also known as Neonatal Fc receptor, heterodimer of FCGRT (Fc Fragment of IgG Receptor and Transporter), encompassing amino acid (24-297) and B2M (beta 2 microglobulin), encompassing amino acids 21-119, respectively. FCGRT has a C-terminal His-tag (10xHis). These recombinant proteins are co-expressed in a HEK293 expression system and affinity purified.
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Synonyms
FCGRT, FCRN, IgG receptor FcRn large subunit p51, IgG Fc fragment receptor transporter alpha chain, Neonatal Fc receptor, Beta-2-microglobulin, Beta-2-microglobulin form pI 5.3, CDABP0092, HDCMA22P
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Product Data Gallery
4-20% SDS-PAGE Coomassie Staining
Product Info
Storage and Usage
Citations
Species
Human
Construct
FCGRT ((24-297)-His) / B2M (21-119)
Host Species/Expression System
HEK293
Purity
≥90%
Format
Aqueous buffer solution
Formulation
8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.
MW
FCGRT: 32 kDa + glycans; B2M: 14 kDa + glycans
Amino Acids
FCGRT: 24-297; B2M: 21-119
Glycosylation
This protein runs at a higher MW by SDS-PAGE due to glycosylation.
Genbank #
FCGRT: NM_001136019; B2M: NM_004048
UniProt #
FCGRT: P55899; B2M: P61769
References
1. Roopenian, D., et al., Nature. 2007 Sep 7: 715-725
2. Shields, R. et al., Biological Chemistry. 2000 Nov; 276:6591-6604.
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