CHD2, GST-tag Recombinant

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Catalog #
55005
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Description

Human chromodomain helicase DNA binding protein 2, or CHD2, (GenBank Accession No. NM_001271) a.a. 260-456(end), with N-terminal GST-tag, MW=49.3 kDa, expressed in an E. coli cell expression system.

Synonyms
chromodomain helicase DNA binding protein 2
Product Info
Storage and Usage
Citations
Species
Human
Host Species/Expression System
E. coli
Purity

≥80%

Format
Aqueous buffer solution
Formulation
40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol
MW
49.3 kDa
Amino Acids
260–456(end)
Genbank #
NM_001271
UniProt #
O14647
Tag(s)
N-terminal GST-tag
Background
The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template.
References

1. Woodage, T., et al., Proc Natl Acad Sci
USA. 1997 Oct 14;94(21):11472-7.
2. Harada, A., et al., EMBO J. 2012 May
8;31(13):2994-3007.