4-(4-(4-(3-fluorobenzyloxy)-3-chlorophenylamino)quinazolin-6-yl)phenol

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Catalog #

82072

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Description

4-(4-(4-(3-fluorobenzyloxy)-3-chlorophenylamino)quinazolin-6-yl)phenol, is a derivative of the quinazoline containing drug Lapatinib. Lapatinib reversibly blocks phosphorylation of the epidermal growth factor receptor (EGFR), ErbB2, and the Erk-1 and-2 and AKT kinases; it also inhibits cyclin D protein levels in human tumor cell lines and xenografts.

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