PFI-3

Catalog #

82070

$350 *

Size: 25 mg

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Bulk/Custom

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*US Pricing only. For international pricing, please contact your local distributor.

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Description

PFI-3 is a selective chemical probe for SMARCA bromodomains that inhibits SMARCA2, SMARCA4 and PB1(5) bromodomains. PFI-3 is a probe that binds avidly to the structurally-similar SMARCA4 bromodomain and PB1(bromodomain 5) with Kd values of 89 and 48 nM, respectively. PFI-3 displays 30-fold selectivity over other sub-family branches and accelerates FRAP recovery in cells at a concentration of 1 μM.

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Synonyms

PFI3, PFI 3

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