SYK Assay Kit
SYK of the nonreceptor tyrosine kinases plays a role in autoimmune diseases like Epstein Barr virus and hematopoietic malignancies. The SYK Assay Kit is designed to measure SYK activity for screening and profiling applications using Kinase-Glo® MAX as a detection reagent.
Need us to run inhibitor screens or profile your compounds against SYK? Check out our Kinase Screening Services.
Kinase-Glo MAX (Promega #V6071)
Dithiothreitol (DTT, 1 M; optional)
Microplate reader capable of reading luminescence
Adjustable micropipettor and sterile tips
30°C incubator
1. Furusho, A., Aoki, H., et al. Involvement of B Cells, Immunoglobulins, and Syk in the Pathogenesis of Abdominal Aortic Aneurysm. J. Amer. Heart Assoc. 2018; 7:e007750.
2. Law, C.L., Chandran, K.A., et al. Phospholipase C-gamma1 interacts with conserved phosphotyrosyl residues in the linker region of Syk and is a substrate for Syk. Mol. Cell Biol. 1996; 16(4):1305-15.
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