Roscovitine

Catalog #

27040

$140 *

Size: 10 mg

Qty

Bulk/Custom

*US Pricing only. For international pricing, please contact your local distributor.

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Description

Roscovitine is a potent inhibitor of p34cdc2 (IC50 = 0.2 µM). Also inhibits p33cdk2 and p33cdk5.

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Synonyms

CYC202, Seliciclib, 6-Benzylamino-2[(R)-(1'-ethyl-2'-hydroxyethylamino)]-9-isopropylpurine, CDK-5

Product Info

Storage and Usage

Citations

Purity

≥99%

Format

White to off-white powder.

Formula

C₁₉H₂₆N₆O

354.5 Da

Solubility

Prepare initial stock solutions in DMSO (soluble at 200 mg/ml) or ethanol (soluble at 200 mg/ml) for in vitro use; solubility in water is low.

CAS Registry #

186692-46-6

References

Havlicek, L., et al. J. Med. Chem. 40: 408-412 (1997).