Rapamycin

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Catalog #

27062

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Description

Immunosuppressant, related to FK-506, but without calcineurin inhibitory activity even when complexed to FK-506 binding protein. Selectively blocks signaling that leads to p70 S6 kinase activation (IC50 = 50 pM).

This product has been cited 3 times.

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Synonyms

Rapamune, Sirolimus

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Product Info

Storage and Usage

Citations3

Purity

98% NMR

Supplied As

White solid

Formula

C₅₁H₇₉NO₁₃

914.17 Da

Solubility

Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 90 mg/ml)

CAS Registry #

53123-88-9

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Rapamycin

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