MMP7 Fluorogenic Assay Kit
The MMP7 (Matrix MetalloProteinase 7) Fluorogenic Assay Kit is designed to measure MMP7 protease activity for screening and profiling applications, in a homogeneous assay with no time-consuming washing steps.
Need us to run inhibitor screens or profile your compounds against MMP7? Check out our Protease Screening Services.
- Fluorescent microplate reader capable of reading λexc/λem=328 nm/393 nm
- Adjustable micropipettor and sterile tips
- 30°C incubator
| Catalog # | Name | Amount | Storage |
| Recombinant MMP7* | 7.5 µg | -80°C | |
| 79919 | 1 mM MMP Substrate | 10 µl | -80°C |
| 79917 | MMP Assay Buffer 1 | 25 ml | -20°C |
| 79685 | Black 96-well plate | 1 | Room Temp |
*The concentration of the protein is lot-specific and will be indicated on the tube.
MMP7 (also known as matrix metalloproteinase 7 or pump-1 protease) is a member of the large family of matrix metalloproteinases (MMP) responsible for the breakdown of extracellular matrix proteins such as casein, collagen, and fibronectin. Most MMPs are secreted as inactive pro-proteins and are activated when cleaved by other extracellular proteinases. MMP7 cleaves fibronectin, gelatin and elastin, but not collagen. MMPs are involved in tissue remodeling and in the escape of metastatic cells from the primary tumor and angiogenesis. MMP7 can activate MMP2 and MMP9, and upregulation of MMP7 is found in many carcinomas. They are candidate therapeutic targets in various diseases related to tissue remodeling including cancer and inflammatory diseases.
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