MMP26 Fluorogenic Assay Kit
The MMP26 (Matrix metalloproteinase 26) Fluorogenic Assay Kit is designed to measure MMP26 protease activity for screening and profiling applications, in a homogeneous assay with no time-consuming washing steps.
Need us to run inhibitor screens or profile your compounds against MMP26? Check out our Protease Screening Services.
- Fluorescent microplate reader capable of reading λexc/λem=328 nm/393 nm
- Adjustable micropipettor and sterile tips
- 30°C incubator
| Catalog # | Name | Amount | Storage |
| Recombinant MMP26* | 1 µg | -80°C | |
| 79919 | 1 mM MMP Substrate | 10 µl | -80°C |
| 79917 | 1x MMP Assay Buffer 1 | 25 ml | -20°C |
| 79685 | Black 96-well plate | 1 | Room Temp |
*The concentration of the protein is lot-specific and will be indicated on the tube.
MMP26 (also known as matrilysin-2 or endometase) is a member of the large family of matrix metalloproteinases (MMP) responsible for the breakdown of extracellular matrix proteins such as collagen. Most MMPs are secreted as inactive pro-proteins and are activated when cleaved by extracellular proteinases. MMP26 cleaves collagen type IV, vitronectin, fibronectin, and fibrinogen, among others. It also cleaves MMP9 for activation. MMPs are involved in tissue remodeling and in the escape of metastatic cells from the primary tumor. They are candidate therapeutic targets in various diseases related to tissue remodeling including cancer.
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