Anti-LAG3, Neutralizing Antibody

Catalog #: 71219
Size: 100 µg
Species: Human
Host Species: HEK293
MW: Heavy chain: 51 kDa Light chain:26kDa
Clonality: Monoclonal
Isotype: IgG1
Neutralizing recombinant human antibody recognizing the Lag-3 binding region.
Assay Conditions:
Anti-LAG3 Neutralizing Antibody was added at various concentrations to the LAG-3/NFAT Reporter Jurkat cells (BPS Cat. #71278) co-cultured with superantigen-loaded Raji cellsand luciferase activity was measured using ONE-Step Luciferase Assay System (BPS Cat. #60690)
8 mM Phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.
Protein A affinity chromatography from HEK293 supernatants.
Storage / Stability:
Stable for at least 12 months at -80°C. Avoid freeze/thaw cycles. Store diluted antibody with carrier protein (BSA 0.1 – 0.5%) at 4°C, stable for 2 weeks.
Useful as a reference antibody for screening LAG-3 neutralizing antibodies.
1. Byrnes, et al., Cytometry A. 2012 Sep;81(2):165-8.

2. Di Carlo, et al., J. Pathol. 2005 Jan; 205(1):82-91.

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