Histone H3/H4 Tetramer (full length), His-tag Recombinant

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Catalog #

52064

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Description

Human recombinant histone tetramer, full length, consisting of 2 molecules each of histones H3 (a.a. 1-136(end)), and H4 (a.a. 1-103(end)), each with an N-terminal His-tag, expressed in an E. coli expression system. GenBank Accession Nos. are NM_003532, and NM_003548, respectively. Global MW = 57 kDa.

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Synonyms

H3/H4

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Product Data Gallery

4-20% SDS-PAGE Coomassie Staining

Product Info

Storage and Usage

Citations

Species

Human

Host Species/Expression System

E. coli

Purity

≥80%

Format

Aqueous buffer solution

Formulation

45 mM Tris pH 7.5, 2 M NaCl, 1 mM EDTA, 1 mM DTT and 10% glycerol.

57 kDa

Genbank #

NM_003532, NM_003548

UniProt #

P68431, P62805

Tag(s)

N-terminal His-tag

Background

The histone tetramer consists of two copies of both histones H3 and H4. It forms the central core of the nucleosome and, as such, plays a prominent role in the assembly, disassembly and positioning of nucleosomes.

References

1. Huang, C., et al., PLoS Genet. 2013; 9(6): 1371.
2. Liu, W.H., et al., Nucleic Acids. 2012; 40(22):11229-39

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Datasheets/Protocols

52064_Lot130926.pdf

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Histone H3/H4 Tetramer (full length), His-tag Recombinant

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