Search results for: 'lag3'

LAG3:FGL1 Assay Service

LAG3 as a Cotherapy for Immune Checkpoints Cotherapy with PD-1 Therapeutic antibodies targeting the immune checkpoint receptors PD-1 and CTLA4 substantially changed the prognosis for many cancer patients.  When successful, these treatments extend lives.  Still, cancer is relentless.  Only a relatively small number of patients respond or have substantial remission when these treatments are used as monotherapies.  Much of the current research on immunomodulating r...

Custom Protein Production Cloning   Expression & Purification Activity Testing Bulk Production   With BPS Bioscience's custom protein development services, we use optimized conditions to generate recombinant proteins with high purity and high yields. Projects are composed of five milestones where data is provided after each milestone completion. Each project is customizable through working directl...

Methods For Drug Discovery   Immunotherapies  based on targeting the  PD-1:PD-L1  immune checkpoint pathway are having clinical impact and are giving new hope to cancer patients. However, positive response to treatment is not guaranteed and resistance remains a concern. Improving outcomes based on immunotherapy requires multiple approaches for manipulating the complexities of the immune system and tumor microenvironment. To meet these challenges, a series of r...

Bioactive Proteins & Enzymes BPS Bioscience specializes in manufacturing bioactive enzymes and protein complexes, offering over 2000 protein products critical for drug discovery. We feature a large selection of epigenetic and metabolic enzymes, kinases and other cell signaling proteins, as well as cancer-related proteins and their mutants, including KRAS, PARP proteins, and immune checkpoint molecules.  Contact us to learn how our products and services can help you reach your resea...

Technical Notes and Application Notes Immunotherapy | Cancer Targets | CAR-T/NK Cell Therapy | Gene & Cell Therapy | Cell Culture | Cancer Pathways | CRISPR/Cas9 | Cell Receptor Targets | Ubiquitination | Protein Conjugation | Technology | Cholesterol Pathways | SARS-CoV-2/COVID-19 Immunotherapy A2aR & Immunotherapy BCMA & Cancer Bispecific Antibodies Combination Therapies for Targetin...

Combining Therapies for Targeting Immune Checkpoints   |  IMMUNE CHECKPOINTS  |           |  KINASES  |                |  PARPS  |              |  HDACS  |               |  CAR T-CELL THERAPY  | Cancer is a balance between the defens...

Custom Lentivirus Services BPS Bioscience has developed a diverse portfolio of lentivirus products to study COVID-19 , cell signaling pathways , CAR T-cell therapy , CRISPR , and immunotherapy . In addition to our product portfolio , we also offer custom services to develop a lentivirus suited for your research needs.  Customizable Options Reporters ( GFP , Luciferase , Dual Reporter ) Antibiotic selection markers ( Puromycin , Hygromycin , G4...

The Promise of NK Cell Therapeutics Introduction NK cells are the first line of defense against cancer and have been in the spotlight as a cancer therapy in the last decade. Their advantages versus T cells, such as their safety profile and not requiring MHC (Major Histocompatibility Complex)-antigen stimulation to become cytotoxic, have made NK cells attractive. However, as with T cells, the TME (tumor microenvironment) can suppress their activity, and infiltration into solid tumors is s...

Citations   This page contains a list of scientific journal articles that have cited BPS products and services since 2013. We would like to congratulate all our loyal customers on their contributions to the scientific community. Our customers are truly amazing and dedicated scientists and this is evidenced by the outstanding research they are doing.  Search By Product Name or Catalog Number Name Title 10X HAT Assay Buffer (50095...

Immune Checkpoint Molecules Immune checkpoint molecules are crucial components of the immune system that regulate the intensity and duration of immune responses but have been usurped by cancer cells and pathogens to evade the immune system. Immune checkpoint molecules are crucial components of the immune system that regulate the intensity and duration of immune responses but have been usurped by cancer cells and pathogens...

Immunotherapy Biochemical Screening Services Immunotherapy is a type of medical treatment that engages the body's immune system to fight diseases, such as cancer, infections, and autoimmune disorders. It works by either stimulating the immune system to attack cancer cells or other disease-causing agents, or by using synthetic proteins or antibodies to target specific molecules on the surface of cancer cells or other pathogens. Immunotherapy has shown prom...