CD28 Screening Services
Cluster of Differentiation 28, or CD28, is a protein which is necessary for the activation and survival of T cells. The CD28 receptor can bind to B7-1 and B7-2, proteins expressed mostly by antigen presenting cells (APCs). The interaction between B7 proteins and CD28 receptors serves as a potential method to enhance anti-tumor immunity by developing therapies that mimic B7 proteins and activate the CD28 receptor. Alternatively, in autoimmune diseases such as ...
Immunotherapy Biochemical Screening Services
Immunotherapy is a type of medical treatment that engages the body's immune system to fight diseases, such as cancer, infections, and autoimmune disorders. It works by either stimulating the immune system to attack cancer cells or other disease-causing agents, or by using synthetic proteins or antibodies to target specific molecules on the surface of cancer cells or other pathogens. Immunotherapy has shown prom...
Citations
This page contains a list of scientific journal articles that have cited BPS products and services since 2013. We would like to congratulate all our loyal customers on their contributions to the scientific community. Our customers are truly amazing and dedicated scientists and this is evidenced by the outstanding research they are doing.
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Name
Title
10X HAT Assay Buffer (50095...
Combining Therapies for Targeting Immune Checkpoints
| IMMUNE CHECKPOINTS | | KINASES | | PARPS | | HDACS | | CAR T-CELL THERAPY |
Cancer is a balance between the defens...
Immune Checkpoint Molecules
Immune checkpoint molecules are crucial components of the immune system that regulate the intensity and duration of immune responses but have been usurped by cancer cells and pathogens to evade the immune system.
Immune checkpoint molecules are crucial components of the immune system that regulate the intensity and duration of immune responses but have been usurped by cancer cells and pathogens...
Enzymatic Biotinylation & BirA
Biotin is a small, water soluble molecule of the vitamin B family. The most attractive property of biotin, from a biotechnological standpoint, is that it binds to avidin and to bacteria-derived streptavidin with an exceptionally high affinity and high specificity. Indeed, the binding of biotin and avidin is among the strongest noncovalent interaction known (dissociation constant in the range of 10 −14 M to 10 −15 M).
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The Promise of NK Cell Therapeutics
Introduction
NK cells are the first line of defense against cancer and have been in the spotlight as a cancer therapy in the last decade. Their advantages versus T cells, such as their safety profile and not requiring MHC (Major Histocompatibility Complex)-antigen stimulation to become cytotoxic, have made NK cells attractive. However, as with T cells, the TME (tumor microenvironment) can suppress their activity, and infiltration into solid tumors is s...
