SIRP-α (SIRP alpha), His-tag, Biotin-labeled (Human) HiP™ Recombinant

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Catalog #

71138

As low as $325 *

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Description

SIRP alpha protein, or Signal regulatory proteinalpha (SIRP-α), also known as Tyrosine protein phosphatase non-receptor type substrate 1, CD172a, Bit, and MyD-1, GenBank Accession No. NM_080792, a.a. 27-370, with C-terminal Avi and His tags, MW 40.3 kDa*, expressed in a HEK293 expression system and enzymatically biotinylated using Avi-tag™ technology. This SIRP alpha protein acts as a receptor for CD47; a.a. 27-370 correspond to the extracellular portion of SIRP-α. *Note: SIRP-α is heavily glycosylated, resulting in higher molecular weight.

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Synonyms

SIRP alpha protein, sirpa protein, sirp-a protein, SIRPa, CD172a, Tyrosine-protein phosphatase non-receptor type substrate 1, CD172a, Bit, and MyD-1,

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Product Data Gallery

4-20% SDS-PAGE Coomassie Staining

Gel Filtration Trace

CD47: SIRP-α[Biotinylated] inhibition curve using a chemiluminescent assay (#72044). Representative data only; data may vary by lot.

Product Info

Storage and Usage

Citations

Species

Human

Host Species/Expression System

HEK293

Purity

≥90%

Supplied As

Aqueous buffer solution.

Formulation

8 mM Phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol

40.3 kDa

Amino Acids

27-370

Genbank #

NM_080792

UniProt #

P78324

Tag(s)

C-terminal His-Avi-Tags

References

1. Hatherley, D., et al., Mol. Cell, 2008, 31:266-77
2. Baba, N., et al., J. Exp. Med., 2013, 210(6):1251-63

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Datasheets/Protocols

71138_Lot_150604.pdf

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SIRP-α (SIRP alpha), His-tag, Biotin-labeled (Human) HiP™ Recombinant

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