Parthenolide

Catalog #

27768-2

$125 *

Size: 50 mg

Qty

Bulk/Custom

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Description

Parthenolide specifically inhibits HDAC1 without affecting other class I/II HDACs.

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Synonyms

(1aR,7aS,10aS,10bS,E)-1a,5-dimethyl-8-methylene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[2',3':9,10]cyclodeca[1,2-b]furan-9(1aH)-one

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Product Data Gallery

Product Info

Storage and Usage

Citations

Format

white to off-white crystalline solid.

Target(s)

HDAC1

Formula

C₁₅H₂₀O₃

248.3 Da

Solubility

Soluble in DMSO (100 mg/ml) or 100% ethanol (20 mg/ml).

CAS Registry #

20554-84-1

Background

Parthenolide is a sesquiterpene lactone and the active principle of feverfew (Chrysanthemum parthenium)

References

1. Gopal, Y.N.V., et al. 2007. Chemistry and Biology 14(7) 813-823.
2. Groenewegen, W.A., et al. 1990. J. Pharm. Pharmacol. 42: 553-557.
3. 2. Sumner, H., et al. 1992. Biochem. Pharmacol. 43: 2313-2320.
4. 3. Barsby, R.W., et al. 1992. J. Pharm. Pharmacol. 44 :737-740.

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Parthenolide

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