FCGR2A (CD32A) Knockout Jurkat Cell Line

Catalog #

78549

$6,500 *

Size: 2 vials

Qty

Bulk/Custom

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*US Pricing only. For international pricing, please contact your local distributor.

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Description

The FCGR2A Knockout Jurkat cell line was generated by CRISPR/Cas9 genome editing to remove FCGR2A (CD32A), the gene encoding protein FcγRIIa (Fragment crystallizable gamma receptor II a, also known as FcGRIIa, Fc-gamma-RIIa, and CD32A).

Purchase of this cell line is for research purposes only; commercial use requires a separate license. View the full terms and conditions.

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Synonyms

FcγRIIA, FCGRIIA

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Product Data Gallery

Expression of FCGR2A (CD32A) in the FCGR2A (CD32A) Knockout Jurkat Cell Line

Genomic Sequencing of FCGR2A (CD32A) in the FCGR2A (CD32A) Knockout Jurkat cells

Product Info

Storage and Usage

Citations

Host Cell Line

Jurkat (clone E6-1), human T lymphoblast, suspension

Supplied As

Each vial contains 2 x 10⁶ cells in 1 ml of cell freezing medium (BPS Bioscience #79796)

Materials Required But Not Supplied

Name	Ordering Information
Thaw Medium 2	BPS Bioscience #60184

UniProt #

P12318

Mycoplasma Testing

The cell line has been screened to confirm the absence of Mycoplasma species.

Background

FCGR2A (also known as CD32A) encodes a low affinity Fc receptor for immunoglobulin G. FcγRIIa is a cell surface receptor expressed on a variety of immune cells such as macrophages and neutrophils. It is involved in phagocytosis and in the clearing of spent immune complexes from the circulation. A polymorphism in FcγRIIa is associated with increased risks of nephritis and lupus.

Storage/Stability

Cells are shipped in dry ice and should immediately be thawed or stored in liquid nitrogen upon receipt. Do not use a -80°C freezer for long term storage.

Growth Media

For best results, it is highly recommended to use these validated and optimized media from BPS Bioscience. Other preparations or formulations of media may result in suboptimal performance.

Thaw Medium 2 (BPS Bioscience #60184): RPMI 1640 medium supplemented with 10% FBS, 1% Penicillin/Streptomycin

Applications

Use as a control for characterizing FCGR2A in T cells

Shipping Temperature

-80°C

Notes

License Disclosure
Visit bpsbioscience.com/license for the label license and other key information about this product.

Troubleshooting Guide
Visit bpsbioscience.com/cell-line-faq for detailed troubleshooting instructions. For all further questions, please email [email protected].

Warnings

Avoid freeze/thaw cycles

Scientific Category

Immunotherapy

Regulatory Status

Research Use Only

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FCGR2A (CD32A) Knockout Jurkat Cell Line

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