Tubacin

Catalog #

27662

$175 *

Size: 1 mg

Qty

Bulk/Custom

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Description

Tubacin is a potent, selective, reversible, and cell-permeable inhibitor of HDAC6 with an IC50 value of 4 nM.

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Synonyms

N-[4-[(2R,4R,6S)-4-[(4,5-diphenyl-1,3-oxazol-2-yl)sulfanylmethyl]-6-[4-(hydroxymethyl)phenyl]-1,3-dioxan-2-yl]phenyl]-N'-hydroxyoctanediamide

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Product Data Gallery

Product Info

Storage and Usage

Citations

Purity

≥95% by HPLC

Supplied As

Solid

Target(s)

HDAC6

Formula

C₄₁H₄₃N₃O₇S

721.86 Da

Solubility

insoluble in EtOH; insoluble in H2O; ≥7.19 mg/mL in DMSO. For obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while.

CAS Registry #

537049-40-4

References

1. Aldana-Masangkay GI, et al. Leuk Lymphoma. 2011 Aug;52(8):1544-55.
2. Kawada J, et al. J Biol Chem. 2009 Jun 19;284(25):17102-9.

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