TROP2 – CHO-K1 Recombinant Cell Line

Catalog #

78099

$7,150 *

Size: 2 vials

Qty

Bulk/Custom

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*US Pricing only. For international pricing, please contact your local distributor.

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Description

Recombinant CHO-K1 cells expressing the cell surface glycoprotein TROP2 (Trophoblast cell-surface antigen 2); ref. seq. NM_002353.2.

Purchase of this cell line is for research purposes only; commercial use requires a separate license. View the full terms and conditions.

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Synonyms

Trophoblast cell-surface antigen 2 cells, TROP 2 cell line, tumor associated calcium signal transducer 2, TACSTD2 recombinant cell line, GA733-1 cell line, M1S1 cells

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Product Data Gallery

FACS Analysis

Product Info

Storage and Usage

Citations

Host Cell Line

CHO-K1

Species

Human

Supplied As

Each vial contains ~ 2 x 10⁶ cells in 1 ml of 10% DMSO in FBS.

Materials Required But Not Supplied

Materials for Cell Culture

Thaw Medium 3 (BPS Bioscience #60186)
Growth Medium 3J (BPS Bioscience #79974)

Materials Required for Cellular Assay

Human TruStain FcX™ (Fc Receptor Blocking Solution) (Biolegend #422302)
PE anti-human TACSTD2 (TROP2) Antibody (Biolegend #363803)
Flow Cytometer

UniProt #

P09758

Mycoplasma Testing

The cell line has been screened using the MycoAlert™ Mycoplasma Detection kit (Lonza, #LT07-218) to confirm the absence of Mycoplasma species.

Background

Trophoblast cell-surface antigen 2 (TROP-2), also referred to as tumor associated calcium signal transducer 2 (TACSTD2), GA733-1 or M1S1, is a cell surface glycoprotein that is highly expressed in a variety of solid cancers, yet has low expression in normal cells. Through a variety of signaling pathways, TROP2 regulates cancer growth and metastasis and is a favorable target for antibody drug conjugates (ADC) and immunotherapy.

Storage/Stability

Cells will arrive upon dry ice and should immediately be thawed or stored in liquid nitrogen upon receipt. Do not use a -80°C freezer for long term storage.

Culture Conditions

For best results, it is highly recommended to use these validated and optimized media from BPS Bioscience. Other preparations or formulations of media may result in suboptimal performance.

Thaw Medium 3 (BPS Bioscience #60186): F-12K Medium supplemented with 10% FBS, 1% Penicillin/Streptomycin

Growth Medium 3J (BPS Bioscience #79974): F-12K Medium supplemented with 10% FBS, 1% Penicillin/Streptomycin plus 5 μg/ml of Puromycin

Shipping Temperature

-80°C

Notes

License Disclosure
Visit bpsbioscience.com/license for the label license and other key information about this product.

Troubleshooting Guide
Visit bpsbioscience.com/cell-line-faq for detailed troubleshooting instructions. For all further questions, please email [email protected].

Scientific Category

CAR-T

Regulatory Status

Research Use Only

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TROP2 – CHO-K1 Recombinant Cell Line

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