Mouse TREM2, also known as Triggering receptor expressed on myeloid cells 2 and Trem2a, GenBank Accession No. NM_031254, a.a. 19-168, fused at the C-terminus to the Fc portion of Human IgG1 and with a C-terminal Avi-tag, expressed in a Hek293 expression system. This protein was biotinylated using AviTag™ technology. MW=45 kDa.
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Synonyms
Triggering receptor expressed on myeloid cells 2, Triggering receptor expressed on monocytes 2, Trem2a, Trem2b, Trem2c
8 mM Phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.
MW
45 kDa + glycans
Amino Acids
19-168
Glycosylation
This protein runs at a higher MW by SDS-PAGE due to glycosylation.
Genbank #
NM_031254
UniProt #
Q99NH8
Tag(s)
Fc-Avi
Label
This protein is enzymatically biotinylated using Avi-Tag™ technology. Biotinylation confirmed to be ≥90%.
For more information on enzymatic biotinylation, please see our Tech Note.
References
1. Guerreiro, R., et al., New England Journal of Medicine. 2013; 368: 117-127.
2. Jonsson, T.., et al., New England Journal of Medicine. 2013; 368: 107-116.
Storage/Stability
At least 6 months at –80°C
Instructions for Use
Thaw on ice and gently mix prior to use. DO NOT VORTEX. Perform a quick spin before opening. Aliquot into small volumes and flash freeze for long term storage. Avoid multiple freeze/thaw cycles.