Sildenafil Citrate
Catalog #
27105
$310
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Description
Sildenafil Citrate, a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5), is a well-tolerated and highly effective treatment for erectile dysfunction.
This product has been cited 2 times.
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Product Info
Storage and Usage
Citations2
Purity
≥99% by HPLC
Format
White to off-white solid.
Formula
C22H30N6O4S•C6H8O7
MW
666.7 Da
Solubility
Insoluble in water; Insoluble in Ethanol; soluble in DMSO (warmed with 50ºC water bath) at 100 mg/mL (149.99 mM)
Biological Activity
Sildenafil exhibited high affinity for PDE type 5 and type 6 with inhibition constants (Ki) of ∼3.5 and 33 nM, respectively.
CAS Registry #
171599-83-0
References
Muneer, A. et al. US Endocrine Disease (2007); 1:92-95.
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