Tadalafil

Catalog #

27657-1

$140 *

Size: 50 mg

Qty

Bulk/Custom

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Description

Tadalafil, also known as IC351 or Cialis, is a potent, reversible and competitive small-molecule inhibitor of phosphodiesterase 5 (PDE5)

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Synonyms

Cialis, ICOS 351, Ic351, IC 351, IC-351, (6R,12aR)-6-(benzo[d][1,3]dioxol-5-yl)-2-methyl-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione

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Product Data Gallery

Product Info

Storage and Usage

Citations

Purity

≥99% by HPLC

Target(s)

PDE5

Formula

C₂₂H₁₉N₃O₄

389.4 Da

Solubility

insoluble in H2O; insoluble in EtOH; ≥16.6 mg/mL in DMSO. For obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while.

CAS Registry #

171596-29-5

References

1. Sawamura, F., et al. J Pharmacol Sci 111, 235-243 (2009)
2. Porst, H. Int. J. Impotence Res. (2002) 14, Suppl 1, S57-S64.
3. Forgue, S.T., et al. Br J Clin Pharmacol (2005); 61(3): 280-288.

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