CD47: Sirpα Screening Services
Cluster of Differentiation 47, or CD47, plays an essential role in cell growth, death, migration, and adhesion. CD47 binding to SIRP-α mediates phagocytosis by sending a “do not eat me” signal to phagocytes. CD47 proteins are often over expressed by tumor cells as a means for them to escape phagocytosis. As a result, cancerous tumor cells have the ability to proliferate and evade the immune system.
BPS Bioscience offers CD47:SIRP-α and CD47:SIRP-ɣ screening services to help accelerate your research and drug discovery programs. This biochemical screen is a fast, reliable, and inexpensive initial screen to identify inhibitors of CD47 binding to SIRP-α and/or SIRP-ɣ. Trust us to provide you with high quality data with fast turnaround time. Our team of experts along with our broad services portfolio make it easy to:
- Screen for inhibitors/targets using our CD47:Sirpα assay
- Select from IC50 determination and single point concentrations
- Receive data within days of compound submission
- Perform follow-up studies using the same soluble receptors manufactured in-house
Get questions answered or project guidance in a time-efficient manner. BPS Biosciences offers a variety of CD47 related products, including
Contact BPS today to find out more about how we can assist you in your CD47 related research.
Assay Format:
Not quite what you're looking for? We also offer custom assays for several other immunotherapy targets. Our Custom Assay Development Services allow for flexibility to meet your specific research needs.
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Related Services
- Screening & Profiling
- Biochemical Assay Development
- Cell-Based Assay Development
- Protein Expression
- Cell Line Development
