Resveratrol

Catalog #

27642-3

$175 *

Size: 500 mg

Qty

Bulk/Custom

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Description

Resveratrol is a phytoalexin produced naturally by several plants with anti-cancer, anti-inflammatory, blood-sugar-lowering and other beneficial cardiovascular effects. Resveratrol activates sirtuin subtype 1 (SIRT-1). SIRT1 activation has been reported to inhibit tumorigenesis and tumor cell proliferation.

This product has been cited 1 time.

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Synonyms

5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol

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Product Data Gallery

Product Info

Storage and Usage

Citations1

Purity

≥98% by HPLC

Target(s)

SIRT1

Formula

C₁₄H₁₂O₃

228.24 Da

Solubility

Soluble in DMSO

CAS Registry #

501-36-0

Background

Resveratrol (also known as SRT-501) is a phytoalexin derived from grapes and other food products with antioxidant and potential chemopreventive activities. Resveratrol induces phase II drug-metabolizing enzymes (anti-initiation activity); mediates anti-inflammatory effects and inhibits cyclooxygenase and hydroperoxidase functions (anti-promotion activity); and induces promyelocytic leukemia cell differentiation (anti-progression activity), thereby exhibiting activities in three major steps of carcinogenesis. This agent may inhibit TNF-induced activation of NF-κB; in a dose- and time-dependent manner.

References

1. Svajger U, et al. Int Rev Immunol. 2012 Jun;31(3):202-22.
2. Whitlock NC, et al. Nutr Cancer. 2012;64(4):493-502.
3. Juan ME, et al. Pharmacol Res. 2012 Jun;65(6):584-91.
4. Turan B, et al. J Bioenerg Biomembr. 2012 Apr;44(2):281-96.

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Resveratrol

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