Recombinant CHO-K1 cells constitutively expressing full length human FcRL5 (Fc Receptor Like 5, also known as CD307, ref. seq. NM_031281).
Purchase of this cell line is for research purposes only; commercial use requires a separate license. View the full terms and conditions.
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Synonyms
Fc receptor-like protein 5, FcR-like protein 5, FcRL5, BXMAS1, Fc receptor homolog 5, FcRH5, Immune receptor translocation-associated protein 2, CD307e, FCRH5, IRTA2
The cell line has been screened to confirm the absence of Mycoplasma species.
Background
FcRL5 is a single-pass type 1 membrane protein which contains 8 immunoglobulin-like C2-type domains. FcRL5 may be involved in B cell development and lymphomagenesis. Moreover, it is enriched in malignant plasma cells of patients diagnosed with multiple myeloma, and is an attractive target for antibody-drug conjugates (ADC), bispecific immune cells engager antibodies, or anti-FcRL5 CAR T cells.
Storage/Stability
Cells are shipped in dry ice and should immediately be thawed or stored in liquid nitrogen upon receipt. Do not use a -80°C freezer for long term storage.
Growth Media
For best results, it is highly recommended to use these validated and optimized media from BPS Bioscience. Other preparations or formulations of media may result in suboptimal performance.
Thaw Medium 3 (BPS Bioscience, #60186): F-12K medium supplemented with 10% FBS, 1% Penicillin/Streptomycin.
Growth Medium 3M (BPS Bioscience, #78377): F-12K medium supplemented with 10% FBS, 1% Penicillin/Streptomycin plus 2.5 µg/ml Puromycin
Applications
Use as target cells for anti-FcRL5 CAR T cells or anti-FcRL5 ADC and bi-specific antibodies
Shipping Temperature
-80°C
Notes
License Disclosure Visit bpsbioscience.com/license for the label license and other key information about this product.