FcER1G Lentivirus

Catalog #

79878

$795 *

Size: 500 µl x 2

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Description

FcER1G is an adapter protein containing an immunoreceptor tyrosine-based activation motif (ITAM) that transduces activation signals from various immunoreceptors. As a component of the high-affinity immunoglobulin E (IgE) receptor, FcER1G mediates allergic inflammatory signaling in mast cells. FcER1G is also a subunit of other Fc receptors.

The human FcER1G Lentiviruses is replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to be transduced into almost all types mammalian cells, including primary and non-dividing cells. The particles contain a FcER1G gene (NM_004106.2) driven by an EF1α promoter (Figure 1).

Figure 1. Schematic of the lenti-vector used to generate the FcER1G lentivirus