SHP-2 Substrate (DiFMUP)
Catalog #
79769
$95
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Description
The fluorogenic SHP-2 substrate, DiFMUP, is added to the mixture of SHP-2 (BPS Bioscience #79018) and SHP-2 Activating Peptide (BPS Bioscience #79319). DiFMU fluorophore is released and can then be measured using a fluorescence reader.
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Synonyms
SHP2, SHP-2
Product Info
Storage and Usage
Citations
Supplied As
DMSO solution
Concentration
1.0 mM
Background
DiFMUP is a fluorinated 4-methylumbelliferyl phosphate (MUP) that is ideal as a substrate for fast, sensitive phosphatase assays, even at low pH.
DiFMUP has an excitation/emission maxima of ~358/450 nm.
References
Welte, S., et al. Anal Biochem. 2005 Mar 1;338(1):32-8.