CD112, His-tag (Human) HiP™ Recombinant

Catalog #

71197

$320 *

Size: 100 µg

Qty

Bulk/Custom

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Description

Human secreted CD112, also known as Nectin-2, Herpes virus entry mediator B, HVEB, PVRL2, and PRR2, GenBank Accession No. NM_002856, a.a. 32-360 with a C-terminal His-tag, expressed in a HEK293 cell expression system. MW = 36.4 kDa (monomer). This protein runs at a higher MW by SDS-PAGE due to glycosylation.

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Synonyms

Nectin-2, Herpes virus entry mediator B, HVEB, PVRL2, and PRR2

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Product Data Gallery

4-20% SDS-PAGE Coomassie Staining

Gel Filtration Curve

CD226:CD112 inhibition curve using an AlphaLISA assay (#72051). Representative data only; data may vary by lot.

Product Info

Storage and Usage

Citations

Species

Human

Host Species/Expression System

HEK293

Purity

≥90%

Format

Aqueous buffer solution

Formulation

8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol

36.4 kDa + glycans

Amino Acids

32-360

Genbank #

NM_002856

UniProt #

Q92692

Tag(s)

C-terminal His-tag

References

1. Bottino, C., et al., J. Exp. Med. 2003; 198(4): 557-567.
2. Pende, D., et al., Blood. 2005; 105(5): 2066-2073.

Storage/Stability

At least 6 months at -80°C

Instructions for Use

Thaw on ice and gently mix prior to use. DO NOT VORTEX. Perform a quick spin before opening. Aliquot into small volumes and flash freeze for long term storage. Avoid multiple freeze/thaw cycles.

Applications

Useful for studying protein binding and screening small molecules.

Shipping Temperature

-80°C

Notes

HiP™ indicates a high purity protein with ≥90% purity as measured by gel filtration.

This protein runs at a higher MW by SDS-PAGE due to glycosylation.

Warnings

Avoid freeze/thaw cycles. Protein may be diluted to 100 μg/ml in PBS + glycerol and stored at -80°C.

Scientific Category

Immunotherapy

Regulatory Status

Research Use Only

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Datasheets/Protocols

71197_Lot150623.pdf

Datasheets provide example lot-specific information. Contact us to request information on currently available lots.

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CD112, His-tag (Human) HiP™ Recombinant

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