PRMT5 & Cancer
Protein arginine methyltransferase 5 ( PRMT5 ) is a critical regulatory protein linked to genome organization, cell cycle regulation, and stem cell differentiation 1 . It forms an active complex with MEP50 and transfers methyl groups from S-adenosylmethoinine (SAM) to histone proteins, transcription factors, and other regulatory proteins. These methylations form mono and symmetrically di-methylated arginine residues. Dysregulation of PRMT5 activity is assoc...
PRMT5/MEP50 Methylation
Comparing Methylation Patterns of Recombinant PRMTs: Abnormal PRMT5/MEP50 Methylation
PRMTs – Roles & Mechanisms
Protein arginine methyltransferase 5 ( PRMT5 ) is a critical regulatory protein linked to genome organization, cell cycle regulation, and stem cell differentiation 1 . It forms an active complex with MEP50 and transfers methyl groups from S-adenosylmethionine (SAM) to histone proteins, transcription factors, and other regula...
Citations
This page contains a list of scientific journal articles that have cited BPS products and services since 2013. We would like to congratulate all our loyal customers on their contributions to the scientific community. Our customers are truly amazing and dedicated scientists and this is evidenced by the outstanding research they are doing.
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10X HAT Assay Buffer (50095...
Metabolic Enzyme Screening & Profiling
Metabolic enzymes that regulate cellular energy pathways are essential for life. This includes all the processes required for material circulation and energy exchange, including catabolism and anabolism of nucleotides, sugars, proteins, and lipids. Metabolic pathway abnormalities have been correlated with diseases, such as diabetes and cancer, and are under investigation for targeted therapeutics.
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Immunotherapy Biochemical Screening Services
Immunotherapy is a type of medical treatment that engages the body's immune system to fight diseases, such as cancer, infections, and autoimmune disorders. It works by either stimulating the immune system to attack cancer cells or other disease-causing agents, or by using synthetic proteins or antibodies to target specific molecules on the surface of cancer cells or other pathogens. Immunotherapy has shown prom...