IgG Antibodies and Fcγ Receptors in Immunotherapy
IgG Antibodies and Fcγ Receptors in Immunotherapy
Monoclonal, immunoglobulin G (IgG), antibodies are the basis of powerful therapies for treating cancer, viral infections, and autoimmune disease. The power of therapeutic antibodies comes from their ability to bind antigen targets with high specificity and then harness the functions of the larger the immune system. There are a variety of immune responses. Cytotoxic anti...
Natural Killer Cells
Natural Killer (NK) cells are lymphocytes involved in the innate immune system that respond to infected cells and tumor cells, limiting these pathologies. They are now considered potential tools for adoptive cell therapies.
Natural Killer (NK) cells are lymphocytes involved in the innate immune system that respond to infected cells and tumor cells, limiting these pathologies. They are now considered potential tools for adoptive cel...
The Promise of NK Cell Therapeutics
Introduction
NK cells are the first line of defense against cancer and have been in the spotlight as a cancer therapy in the last decade. Their advantages versus T cells, such as their safety profile and not requiring MHC (Major Histocompatibility Complex)-antigen stimulation to become cytotoxic, have made NK cells attractive. However, as with T cells, the TME (tumor microenvironment) can suppress their activity, and infiltration into solid tumors is s...
Cell-Based Assays and Expression Kits
Cells can be engineered to serve as readouts for cell-based assays as a complement or alternative to biochemical assays. A variety of cell-based assay types can be used for research and development applications, including signaling pathway analysis, inhibitor/activator studies, CAR-T cell functional screening, ADCC assays, high-throughput screening systems and much more. We provide a variety of cell-based assay express...
Claudin-18: A Therapeutic Target in Oncology
Claudins, a family of small tetraspan proteins expressed in a tissue or cell-specific manner, are major components of the multimeric protein architecture of tight junctions, which prevent ions or small molecules from passing freely between epithelial or endothelial cells. These proteins contain four transmembrane domains mainly responsible for interacting side-to-side with neighboring proteins. Two extracellular loops regulate p...
Citations
This page contains a list of scientific journal articles that have cited BPS products and services since 2013. We would like to congratulate all our loyal customers on their contributions to the scientific community. Our customers are truly amazing and dedicated scientists and this is evidenced by the outstanding research they are doing.
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10X HAT Assay Buffer (50095...
