AAV and Gene Therapy
Introduction
Adeno-Associated Viruses (AAV) have become a prominent tool for gene delivery and have been used with success to treat diseases where a gene is missing, requires editing or silencing, and to increase longevity. The ability to manipulate its capsids, for instance, has advanced the gene therapy (GT) field. Here we will discuss AAV biology, its applications in gene therapy, and current challenges.
AAV Biology
AAV were initially found as contaminants...
