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Support Products & Consumables  Off-the-Shelf Solutions and Kits for Cell and Protein Analysis In scientific experimentation, even basic components such as buffers and reagents can have a significant influence on the integrity of experimental outcomes. Accurate preparation and proper selection of buffers are crucial for achieving consistent and reliable results. For instance, in processes like cell lysis, the choice of the appropriate buffer can ...

Custom Biochemical Assay Development BPS Bioscience has the capability to develop robust biochemical assays using our portfolio of assay technologies. Our biochemical assay development services enable you to generate an appropriate assay which is suitable for screening and evaluating your target of interest. Our cross-functional team of scientists can also work closely with you to develop assays for compound library screening as well as for secondary screening support. ...

Trademarks BPS Bioscience trademarks: Chemi-Verse™  ChoosE2-Opti™ ChoosE3-Freedom™ DUB-Freedom™ Fluoro-Verse™ GroovyGreen™ HiP™ Lumi-Verse™ LysA™ Maxisorp™ ONE-Step™ PARPtrap™ QuickDetect™ Quick PCR™ RediSolution™ StemBright™ Super Western™ TCellM ™ Transfection Collection™ Trademarks of other companies referenced on this website: ADP-Glo and Kinase-Glo are registered trade...

BPS Bioscience Assay Kits At the heart of our assay kits are highly active, purified proteins. These quality proteins are then optimized with ancillary reagents and buffers to produce robust, consistent, and simple-to-use assay kits. Our kits make screening for inhibitory compounds or blocking antibodies simple and accurate. We regularly i...

Cell Isolation Kits Our cell isolation kits allow for fast, simple, and efficient isolation of specific immune cell subsets. Optimized for the isolation of cells from normal human peripheral blood mononuclear cells (PBMCs), our kits use magnetic bead: antibody complexes to separate target antigen-expressing cells from heterogeneous cell populations. For positive selection kits, cells are incubated with the antibody:bead complexes and then p...

Virus-Based Tools Virus-based tools such as Lentivirus, Adeno-Associated Virus (AAV), and Vesicular Stomatitis Virus (VSV) are critical for cell engineering and the study of viral infection.  We have designed a suite of ready-to-use viral reagents to address a wide span of research areas including virology (particularly Coronaviruses), immunotherapy, CAR-T therapy, CRISPR, cell signaling, and more.        Lentiviruses Ideal for pseudotyp...

Protein Frequently Asked Questions FAQ Topic: -Any- General Questions KRAS FAQ Search: How do I thaw recombinant proteins? Thaw on ice and gently mix prior to use. DO NOT VORTEX. Perform a quick spin before opening the tube. Avoid multiple freeze/thaw cycles. Enzymes are particularly sensitive to freeze/thaw and may lose some activity if thawed again. When proteins are diluted to perform an assay do not freeze and re-use the diluted protein. ...

New Customer Discount Program Make the most out of your first order with us. Place your first order with us as a new customer and get up to a 50% discount . Some restrictions apply. Terms For new US customers only. 10% discount  on Assay Kits , Lentiviruses , and Cell Lines . 30% discount  on ONE-Step™ Luciferase Assay System ( #60690 ), TWO-Step Luciferase (Firefly & Renilla) Assay System ( #60683 ), Western EC...

Bioactive Proteins & Enzymes BPS Bioscience specializes in manufacturing bioactive enzymes and protein complexes, offering over 2000 protein products critical for drug discovery. We feature a large selection of epigenetic and metabolic enzymes, kinases and other cell signaling proteins, as well as cancer-related proteins and their mutants, including KRAS, PARP proteins, and immune checkpoint molecules.  Contact us to learn how our products and services can help you reach your resea...

Cell Lines and Primary Cells Cell lines are extremely useful tools for the study of protein interactions, gene activation, cell signaling, viral infection, cell-to-cell communication, and other biological processes in the context of an intact cell system rather than cell-free biochemical assays. BPS Bioscience has developed over 250 stable cell lines applicable across a wide range of research areas including immunotherapy, CAR-T cell therapy, cell signaling, metabolism, neuroscience, and mu...

Research Applications for Engineered iPS Cells Introduction New avenues of research were dramatically opened by the discovery of Takahashi and Yamanaka in 2006 that the ectopic expression of Oct4 (octamer-binding transcription factor 4), Sox2 (SRY-box2), Kfl4 (Kruppel-like factor 4) and c-Myc was sufficient to reprogram terminally differentiated cells into induced pluripotent stem (iPS) cells. These have infinite expansion potential and similar genetic markers, epigenetics and multilineag...

Lentiviruses for SARS-CoV-2 Research To understand the mechanism of SARS-CoV-2 cell entry, it is essential to study how Spike proteins interact with the ACE2 receptor. However, such studies are hampered by the danger of producing and manipulating live coronavirus. A safer alternative to using live coronavirus is to use recombinant lentivirus pseudotyped with the coronavirus S protein. The Spike pseudotyped lentivirus includes a luciferase reporter, allowing the monitoring of viral entry into...

Frequently Asked Questions BPS Bioscience is here to answer your questions and provide project guidance. On the following pages, we outline some of the most frequently asked questions separated by product type. If your question is not answered through these resources, please contact us today and we are happy to assist.  Proteins Cell Lines Assay Kits ...

The Promise of NK Cell Therapeutics Introduction NK cells are the first line of defense against cancer and have been in the spotlight as a cancer therapy in the last decade. Their advantages versus T cells, such as their safety profile and not requiring MHC (Major Histocompatibility Complex)-antigen stimulation to become cytotoxic, have made NK cells attractive. However, as with T cells, the TME (tumor microenvironment) can suppress their activity, and infiltration into solid tumors is s...

Assay Kit Frequently Asked Questions FAQ Topic: -Any- General Technical Questions IC50 Questions Fluorescence Polarization AlphaLISA® TR-FRET Luminescence FAQ Search: Do ...