SARS-CoV-2 Accessory Proteins & ORF9b
Coronavirus SARS-CoV-2 is an enveloped virus that interacts with host cells via a protruding protein called Spike , and fuses with the cellular membrane to inject its genome into the cell. The SARS family of coronaviruses contain a large single stranded RNA genome of about 30 kb with both unique and conserved features compared to other coronaviruses [1].
The presence of a 5′ methylated cap and a 3′ poly-adenylated tail allows the posit...
Mechanism of JAK-STAT Signaling in Cancer
Cell Signaling Pathways
Understanding cell to cell communication through cytokines and other secreted factors is at the center of daily life for countless pharmaceutical researchers. This is because cytokine-based communication is central to normal development and is often a dysfunctional step in cancer and autoimmune diseases ( 1, 2 ). It is also of increasing importance because cytokine release syndrome is a leading caus...
The Promise of NK Cell Therapeutics
Introduction
NK cells are the first line of defense against cancer and have been in the spotlight as a cancer therapy in the last decade. Their advantages versus T cells, such as their safety profile and not requiring MHC (Major Histocompatibility Complex)-antigen stimulation to become cytotoxic, have made NK cells attractive. However, as with T cells, the TME (tumor microenvironment) can suppress their activity, and infiltration into solid tumors is s...
Citations
This page contains a list of scientific journal articles that have cited BPS products and services since 2013. We would like to congratulate all our loyal customers on their contributions to the scientific community. Our customers are truly amazing and dedicated scientists and this is evidenced by the outstanding research they are doing.
Search By Product Name or Catalog Number
Name
Title
10X HAT Assay Buffer (50095...
