MK-1775

Catalog #

82196

$200 *

Size: 10 mg

Qty

Bulk/Custom

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*US Pricing only. For international pricing, please contact your local distributor.

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Description

MK-1775, also known as Adavosertib and AZD1775, is a potent and selective inhibitor of Wee1 with IC50 of 5.2 nM

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Synonyms

Adavosertib, AZD1775, 1-[6-(2-hydroxypropan-2-yl)pyridin-2-yl]-6-[4-(4-methylpiperazin-1-yl)anilino]-2-prop-2-enylpyrazolo[3,4-d]pyrimidin-3-one

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Product Data Gallery

Chemical Structure

Product Info

Storage and Usage

Citations

Purity

≥99%

Format

Solid

Target(s)

Wee1

Formula

C₂₇H₃₂N₈O₂

500.6 Da

Solubility

≥25.03 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH For obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while. Long-term storage in solution is not recommended. Not stable in diluted solutions.

CAS Registry #

955365-80-7

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MK-1775

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