MEG-2 (PTPN9), GST-tag Recombinant
Catalog #
30020
$325
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Description
Human MEG-2, also known as, Protein Tyrosine Phosphatase Non-Receptor Type 9 (PTP-9) and PTPase-MEG2, Genbank Accession No.: M83738, a.a. 285-593(end) with N-terminal GST-tag, expressed in an E. coli expression system. MW=60 kDa.
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Synonyms
MEG2, MEG-2, PTPN9
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Product Data Gallery
Product Info
Storage and Usage
Citations
Species
Human
Host Species/Expression System
E. coli
Purity
≥90%
Format
Aqueous buffer solution
Formulation
25 mM Tris-HCl, pH 8.0, 67 mM NaCl, 1.4 mM KCl, 50% glycerol, 10 mM glutathione, and 3 mM DTT.
MW
60 kDa
Amino Acids
285-593(end)
Specific Activity
1000 pmole/min/µg
Genbank #
M83738
UniProt #
P43378
Background
This PTP contains an N-terminal domain that shares a significant similarity with yeast SEC14, which is a protein that has phosphatidylinositol transfer activity and is required for protein secretion through the Golgi complex in yeast. This PTP was found to be activated by polyphosphoinositide, and is thought to be involved in signaling events regulating phagocytosis.
References
1. Q. Ying, et al., J. Cell Biochem. 2002, 86: 79.
2. H. Huynh, et al. J. Immunol. 2003, 171: 6661.
2. H. Huynh, et al. J. Immunol. 2003, 171: 6661.