MAOA, His-tag, FLAG-Tag Recombinant

Catalog #

71103

$505 *

Size: 20 µg

Qty

Bulk/Custom

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Description

Recombinant human MAOA (monoamine oxidase A), encompassing amino acids 2-497. This construct contains an N-terminal His-tag (6xHis) followed by a Flag-tag. The recombinant protein was affinity purified.

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Synonyms

Monoamine Oxidase A, MAOA, Amine Oxidase A, EC 1.4.3.4, Mao

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Product Data Gallery

4-20% SDS-PAGE Coomassie Staining

Product Info

Storage and Usage

Citations

Species

Human

Construct

MAOA (His-FLAG-2-497)

Host Species/Expression System

Sf9

Purity

≥90%

Format

Aqueous buffer solution

Formulation

40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 0.04% Tween-20, 20% glycerol, and 100 µg/ml FLAG Peptide

58 kDa

Amino Acids

2–497

Genbank #

NM_000240

UniProt #

P21397

Tag(s)

N-terminal His-tag, N-terminal FLAG-tag

Background

Monoamine Oxidases (MAO) catalyze the oxidation of monoamines such as dopamine, serotonin and adrenalin. They are found bound to the outer membrane of mitochondria in most cell types in the body. Two subtypes of monoamine oxidase have been identified: MAO-A and MAO-B. Both are found in neurons and astroglia, with MAO-A also found in the liver, gastrointestinal tract and placenta and MAO-B in blood platelets. Abnormal regulation of MAOs in the body has been associated with depression, substance abuse, attention deficit disorder, and irregular sexual maturation. Mutation of this gene results in Brunner syndrome. This gene has also been associated with a variety of other psychiatric disorders, including antisocial behavior. Alternatively spliced transcript variants encoding multiple isoforms have been observed.

References

1. Hodorova, I., et al., Med. Sci. Monit. 2012;18(12):BR482-BR486.
2. Brunner, H.G., et al., Science. 1993;262(5133):578-580.

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Datasheets/Protocols

71103 Lot 221018-F

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MAOA, His-tag, FLAG-Tag Recombinant

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