Human factor Xa
Catalog #
80112
$450
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Description
The Human Factor Xa was activated from Human Factor X by activation with Russell’s Viper Venom. This RVV-X was removed after activation. Complete activation is observed on SDS-PAGE. MW = 46 kDa.
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Synonyms
FXA, Prothrombinase, Stuart Prower factor, factor Xa
Product Info
Storage and Usage
Citations
Species
Human
Supplied As
Supplied as 0.80 mg total protein in 0.365 ml
Purification
Purified from human plasma that was tested and found negative by FDA-accepted methods for Anti-HIV1/2, Anti-HTLV I & II, HBsAg, Anti-HCV, Syphilis, HBC Ab, HIV-1 p24 Ag or HIV-1 RNA, HCV RNA and HBV RNA. Donors are screened for CJD (Creutzfeldt-Jakob Disease).
Format
Aqueous buffer solution
Formulation
20 mM Bis Tris, 0.7 M NaCl, pH 6.0
MW
46 kDa
Specific Activity
244 IU/mg
UniProt #
P00742
Background
Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting.
References
1. Bondarenko M, et al. J Pharm Pharm Sci. 2013;16(1):74-88.
2. Talbot K, et al. Biochim Biophys Acta. 2013 Jun;1834(6):989-95.
2. Talbot K, et al. Biochim Biophys Acta. 2013 Jun;1834(6):989-95.
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