Dyphylline
Catalog #
27747
$130
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Description
Dyphylline is a PDE inhibitor and a bronchodilator used to treat and/or prevent the symptoms of bronchial asthma, chronic bronchitis, and emphysema.
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Synonyms
Dyphylline; Dilor; Lufyllin; diprophylline
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Product Data Gallery
Product Info
Storage and Usage
Citations
Target(s)
PDE
Formula
C10H14N4O4
MW
254.2 Da
Solubility
Soluble in water (> 100 mM). Prepare solutions immediately before use.
CAS Registry #
479-18-5
Background
Dyphylline is a selective A1 and A2 adenosine receptor antagonist. Decreases ABCG2 protein in cells and inhibits mPGES-1 (IC50 = 200 µM). Shows bronchodilatory and vasodilatory effects in vivo.