CREBBP (KAT3A), GST-tag Recombinant

Catalog #

31128

$305 *

Size: 100 µg

Qty

Bulk/Custom

Add to Favorites

*US Pricing only. For international pricing, please contact your local distributor.

●

Purchase

●

Description

Human bromodomain CREB binding protein (CREBBP), also known as CBP, RSTS and KAT3A, GenBank Accession No. NM_004380, a.a. 1081-1197 corresponding to single bromodomain with N-terminal GST-tag, MW=41 kDa, expressed in an E. coli expression system.

●

Synonyms

CREBBP, CREB binding protein, CBP, RSTS, KAT3A

●

Product Data Gallery

4-20% SDS-PAGE Coomassie Staining

Inhibition of CREBBP with CPB112

CREBBP inhibition curves using a TR-FRET assay (#32619). Representative data only; data may vary by lot.

Product Info

Storage and Usage

Citations

Species

Human

Host Species/Expression System

E. coli

Purity

≥90%

Format

Aqueous buffer solution

Formulation

40 mM Tris-HCl pH 8.0, 110 mM NaCl, 2.2 mM KCl, 0.04% Tween-20 and 20% glycerol.

41 kDa

Amino Acids

1081–1197

Genbank #

NM_004380

UniProt #

Q92793

Tag(s)

N-terminal GST-tag

References

1. Panagopoulos, I., et al., Hum Mol Genet. 2001 Feb 15;10(4): 395-404
2. Huang, W.C., et al., Mol Cell. 2007 Apr 13; 26(1):75-87

Storage/Stability

>6 months at –80°C.

Assay Conditions

Assay was performed using the BPS Bioscience CREBBP Inhibitor Screening Assay Kit (Catalog #32607) following the manufacturer's instructions.

Instructions for Use

Thaw on ice and gently mix prior to use. DO NOT VORTEX. Perform a quick spin before opening. Aliquot into small volumes and flash freeze for long term storage. Avoid multiple freeze/thaw cycles.

Applications

Useful for the study of bromodomain binding assays, screening inhibitors, and selectivity profiling.

Shipping Temperature

dry ice

Warnings

Avoid freeze/thaw cycles.

Scientific Category

Bromodomain

Regulatory Status

Research Use Only