TL1A:DR3 - A Pathway for Immunomodulation
Introduction
The TL1A:DR3 pathway stands as a promising frontier in immunomodulation, offering insights into novel therapeutic interventions for various autoimmune diseases, inflammatory disorders, and cancer. This technical note explores the intricate mechanisms underlying TL1A:DR3 signaling, its physiological roles, and its potential applications in clinical settings. By elucidating the complexities of this pathway, researchers and clinicians c...
Cell Signaling Pathway Screening & Profiling
In order to determine effectors of cell signaling pathways in the context of intact functioning cells, cell-based reporter assays are an ideal option. Using luciferase reporters downstream of a pathway-specific promoter response element, signaling activity can be conveniently measured by the output of luciferase activity. The system can be applied across a wide variety of cell types and signaling pathways and allows for ...
