BAFF-R – CHO K1 Recombinant Cell Line (High, Medium or Low Expression)

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Catalog #

79921

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Description

Recombinant human BAFF-R-CHO K1 cell line stably expressing full length human BAFF-R/TNFRSF13C receptor (GenBank Accession: NM_052945.3). Surface expression of BAFF-R was confirmed by flow cytometry. Each stable clonal cell line was selected for different levels of BAFF-R expression (High, Medium, Low) to mimic different stages of cancer target cells with various BAFF-R expression levels.

Purchase of this cell line is for research purposes only; commercial use requires a separate license. View the full terms and conditions.

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Synonyms

B-cell activating factor receptor cell line, TNFRSF13C cell line, BAFF cell line

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Product Data Gallery

Flow cytometry analysis of cell surface expression of BAFF-R in CHO K1 cells

Product Info

Storage and Usage

Citations

Host Cell Line

CHO K1 cell line, Chinese Hamster Ovary

Species

Human

Supplied As

Each vial contains ~ 2 x 10⁶ cells in 1 ml of 10% DMSO in FBS.

Genbank #

NM_052945.3

UniProt #

Q96RJ3

Mycoplasma Testing

This cell line has been screened using the MycoAlert™ Mycoplasma Detection Kit (Lonza, #LT07-118) to confirm the absence of Mycoplasma contamination. MycoAlert Assay Control Set (Lonza, #LT07-518) was used as a positive control.

Background

BAFF Receptor (B-cell activating factor receptor, BAFF-R) is an essential factor for B cell maturation and survival. In humans it is encoded by the TNFRSF13C gene. BAFF-R function is impressively documented in humans by a homozygous deletion, which leads to an almost complete block of B cell development at the stage of immature/transitional B cells. The resulting immunodeficiency is characterized by B-lymphopenia, agammaglobulinemia, and impaired humoral immune responses.

Storage/Stability

Store in liquid nitrogen immediately upon receipt.

Culture Conditions

For best results, it is highly recommended to use these validated and optimized media from BPS Bioscience. Other preparations or formulations of media may result in suboptimal performance.

Thaw Medium 3 (BPS Bioscience, #60186): F-12K Medium supplemented with 10% FBS, 1% Penicillin/Streptomycin

Growth Medium 3B (BPS Bioscience, #79529): F-12K Medium supplemented with 10% FBS, 1% Penicillin/Streptomycin plus 500 ug/ml Hygromycin B

Instructions for Use

See assay protocol for detailed instructions.

Shipping Temperature

-80°C

Notes

License Disclosure
Visit bpsbioscience.com/license for the label license and other key information about this product.

Troubleshooting Guide
Visit bpsbioscience.com/cell-line-faq for detailed troubleshooting instructions. For all further questions, please email [email protected].

Warnings

Avoid freeze/thaw cycles.

Scientific Category

Immunotherapy

Regulatory Status

Research Use Only