Anti-VISTA Neutralizing Antibody
Catalog #
101293
$450
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Description
This human monoclonal antibody recognizes human V-domain immunoglobulin (Ig) suppressor of T cell activation (VISTA), and neutralizes its interaction with VSIG3 (also called IGSF11). VISTA is also known as B7-H5 or VSIR (GenBank Accession No. NM_022153). VSIG3 is a ligand involved in cell adhesion as a VISTA binding partner. This neutralizing antibody has been functionally tested using the “VSIG-3:VISTA [Biotinylated] Inhibitor Screening Assay Kit” (BPS Bioscience #79782).
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Synonyms
V-type immunoglobulin domain-containing suppressor of T-cell activation, Platelet receptor Gi24, Stress-induced secreted protein-1, Sisp-1, V-set domain-containing immunoregulatory receptor, V-set immunoregulatory receptor, VSIR, C10orf54, SISP1, VISTA, P
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Product Data Gallery
Product Info
Storage and Usage
Citations
Isotype
Human IgG1
Format
Aqueous buffer solution
Formulation
8 mM phosphate pH 7.4, 110 mM NaCl, 2.2 mM KCl, 20% glycerol
Specificity
The antibody recognizes a unique epitope on the surface of human VISTA protein. It has not been tested on other species
MW
~150 kDa
UniProt #
Q9H7M9