TIM-3, Fc fusion (Human) Recombinant

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Catalog #
71151
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Description

Human secreted TIM-3, Fc fusion protein, also known as T-cell immunoglobulin mucin receptor 3, T-cell membrane protein 3, T-cell and immunoglobulin and mucin domain-containing protein 3, TIMD-3, Hepatitis A virus cellular receptor 2, and HAVCR-2. GenBank Accession No. NM_032782.4, a.a. 22-200 expressed in a HEK293 cell expression system. MW = 46.5 kDa. This protein runs at a higher MW by SDS-PAGE due to glycosylation.

This product has been cited 3 times.

Synonyms
tim3, tim, T-cell immunoglobulin mucin receptor 3, T-cell membrane protein 3, T-cell and immunoglobulin and mucin domain-containing protein 3, TIMD-3, Hepatitis A virus cellular receptor 2, HAVCR-2, Tim
Product Info
Storage and Usage
Citations3
Species
Human
Host Species/Expression System
HEK293 cells
Purity

≥90%

Format
Aqueous buffer solution
Formulation
40 mM Tris, pH 8.0, 110 mM NaCl, 2.4 mM KCl, and 20% glycerol.
MW
46.5 kDa
Endotoxin Level

<1 EU/µg

Amino Acids
22-200
Genbank #
NM_032782.4
UniProt #
Q8TDQ0
Tag(s)
C-terminal Fc fusion (Human IgG1)
References

1. Zhu, C. et al., Nat. Immunol. 2005; 6:1245-1252.
2. Anderson, A.C. et al., Science. 2007; 318(5853):1141-1143.