PRL3 (2-173), His-tag Recombinant

Catalog #
30002
$325 *
Size: 50 µg
Qty
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Description

Human PRL 3 (GenBank Accession No. NM_032611), a.a. 2-173 with N-terminal His-tag, MW = 19.5 kDa, expressed in an E. coli expression system.

Synonyms
PRL-3, PTP4A3, PTPIVa, PTPCAAX3, Phosphatase Of Regenerating Liver 3
Product Info
Storage and Usage
Citations
Species
Human
Host Species/Expression System
E. coli
Purity

≥90%

Format
Aqueous buffer solution
Formulation
40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2mM KCl, 20% glycerol, and 3 mM DTT.
MW
19.5 kDa
Amino Acids
2–173
Specific Activity
0.53 pmol/min/µg
Genbank #
NM_032611
UniProt #
O75365
Tag(s)
N-terminal His-tag
Background
Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. May be involved in the progression of cardiac hypertrophy by inhibiting intracellular calcium mobilization in response to angiotensin II.
References
1. Dai N. et al., World J. Gastroenterol. 15 (12), 1499-1505 (2009).
2. Radke I. et al., Br. J. Cancer 95 (3), 347-354 (2006).