Okadaic Acid

Catalog #

27047

$165 *

Size: 100 µg

Qty

Bulk/Custom

*US Pricing only. For international pricing, please contact your local distributor.

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Description

Potent inhibitor of protein phosphatases, especially the PP-1 and PP-2 classes, in numerous cell types. Non-phorbol type tumor promoter.

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Synonyms

Halochondrine A

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Product Data Gallery

Chemical Structure

Product Info

Storage and Usage

Citations

Purity

≥98%

Format

Crystalline solid or clear, colorless solid film or powder

Formula

C₄₄H₆₈O₁₃

805.0 Da

Solubility

Soluble at 2.5% in methanol and ethanol to give a clear, colorless solution.

Biological Activity

Okadaic acid increases intracellular protein phosphorylation and acts as a potent tumor promoter.

CAS Registry #

78111-17-8

References

1. Cohen, P., et al. Trends Biochem. Sci. 15: 98-102 (1990).
2. Suganuma, M., et al. Proc. Natl. Acad. Sci. USA 85: 1768-1771 (1988).